BDBM2574 3-[(2-tert-butylphenyl)sulfanyl]-4-hydroxy-6-phenyl-2H-pyran-2-one::4-hydroxy-6-phenylpyranone 22::CHEMBL263995

SMILES CC(C)(C)c1ccccc1Sc1c(O)cc(oc1=O)-c1ccccc1

InChI Key InChIKey=XGPLSSMARBREMF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 2574   

TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM2574(3-[(2-tert-butylphenyl)sulfanyl]-4-hydroxy-6-pheny...)
Affinity DataIC50: 17nMpH: 4.7 T: 2°CAssay Description:For determination of IC50 values, HIV-1 protease was added to assay buffer containing inhibitor and the substrate (H-His-Lys-Ala-Arg-Val-Leu- (p-NO2)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM2574(3-[(2-tert-butylphenyl)sulfanyl]-4-hydroxy-6-pheny...)
Affinity DataIC50: 17nMpH: 4.7Assay Description:In vitro binding affinity to HIV protease was determined at pH 4.7More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed