BDBM25734 4-[(adamantan-1-ylcarbamoyl)amino]butanoic acid::CHEMBL419810::Urea-based compound, 15

SMILES OC(=O)CCCNC(=O)NC12CC3CC(CC(C3)C1)C2

InChI Key

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 25734   

TargetEpoxide hydrolase B(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
University of Alberta

LigandPNGBDBM25734(CHEMBL419810 | 4-[(adamantan-1-ylcarbamoyl)amino]b...)
Affinity DataIC50: 1.85E+4nMpH: 7.0 T: 2°CAssay Description:Enzyme activity was measured by monitoring the appearance of fluorescent product, 6-methoxy-naphthaldehyde (ex@330 nm and em@ 465 nm) on a SpectraMax...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2008
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Mouse)
University of California Davis

Curated by ChEMBL
LigandPNGBDBM25734(CHEMBL419810 | 4-[(adamantan-1-ylcarbamoyl)amino]b...)
Affinity DataIC50: 2.20E+4nMAssay Description:Tested for 50 % inhibitory concentration against mouse soluble epoxide hydrolase (sEH)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
University of California Davis

Curated by ChEMBL
LigandPNGBDBM25734(CHEMBL419810 | 4-[(adamantan-1-ylcarbamoyl)amino]b...)
Affinity DataIC50: 3.70E+4nMAssay Description:Tested for 50 % inhibitory concentration against human soluble epoxide hydrolase (sEH)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Mouse)
University of California Davis

Curated by ChEMBL
LigandPNGBDBM25734(CHEMBL419810 | 4-[(adamantan-1-ylcarbamoyl)amino]b...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of mouse recombinant soluble Epoxide hydrolaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
University of California Davis

Curated by ChEMBL
LigandPNGBDBM25734(CHEMBL419810 | 4-[(adamantan-1-ylcarbamoyl)amino]b...)
Affinity DataIC50: 684nMAssay Description:Inhibition of human soluble epoxide hydrolase pre-incubated for 5 mins at 30 degC before CMNPC fluorescent substrate addition by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed