BDBM25724 2-[(5-{[4-(2-hydroxyethyl)piperazin-1-yl]methyl}pyridin-2-yl)amino]-1,3-thiazole-5-carbonitrile::aminothiazole analogue, 73

SMILES OCCN1CCN(Cc2ccc(Nc3ncc(s3)C#N)nc2)CC1

InChI Key InChIKey=JRCSXNCOIGABEA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 25724   

TargetAurora kinase A(Human)
Novartis

LigandPNGBDBM25724(2-[(5-{[4-(2-hydroxyethyl)piperazin-1-yl]methyl}py...)
Affinity DataIC50: 5.40E+3nMAssay Description:The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...More data for this Ligand-Target Pair
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Date in BDB:
11/24/2008
Entry Details Article
PubMed