BDBM25721 4-({6-[(5-cyano-1,3-thiazol-2-yl)amino]pyridin-3-yl}methyl)-N-methylpiperazine-1-carboxamide::aminothiazole analogue, 70

SMILES CNC(=O)N1CCN(Cc2ccc(Nc3ncc(s3)C#N)nc2)CC1

InChI Key InChIKey=BUJZOJYQGPNMOP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 25721   

TargetAurora kinase A(Human)
Novartis

LigandPNGBDBM25721(4-({6-[(5-cyano-1,3-thiazol-2-yl)amino]pyridin-3-y...)
Affinity DataIC50: 880nMAssay Description:The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2008
Entry Details Article
PubMed