BDBM2572 2-(4-{4-hydroxy-2-oxo-3-[(2-phenylethyl)sulfanyl]-2H-pyran-6-yl}phenoxy)acetic acid::4-hydroxy-6-phenylpyranone 19

SMILES OC(=O)COc1ccc(cc1)-c1cc(O)c(SCCc2ccccc2)c(=O)o1

InChI Key InChIKey=ZWVMLEVADZPJBJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 2572   

TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM2572(2-(4-{4-hydroxy-2-oxo-3-[(2-phenylethyl)sulfanyl]-...)
Affinity DataIC50: 160nMpH: 4.7 T: 2°CAssay Description:For determination of IC50 values, HIV-1 protease was added to assay buffer containing inhibitor and the substrate (H-His-Lys-Ala-Arg-Val-Leu- (p-NO2)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Universiti Sains Malaysia

Curated by ChEMBL
LigandPNGBDBM2572(2-(4-{4-hydroxy-2-oxo-3-[(2-phenylethyl)sulfanyl]-...)
Affinity DataIC50: 160nMAssay Description:Inhibition of HIV-1 proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed