BDBM256943 US9493432, 69

SMILES Fc1ccc2nc(N[C@H]3CCC[C@@H]3NC(=O)c3c(F)cccc3-n3nccn3)sc2c1

InChI Key InChIKey=FPDPSCDIBFNYTN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 256943   

TargetOrexin/Hypocretin receptor type 1(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM256943(US9493432, 69)
Affinity DataIC50: 15nMT: 2°CAssay Description:Orexin antagonist activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2017
Entry Details
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TargetOrexin receptor type 2(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM256943(US9493432, 69)
Affinity DataIC50: 3.20E+3nMT: 2°CAssay Description:Orexin antagonist activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2017
Entry Details
Go to US Patent