BDBM25689 4-[(5-bromo-1,3-thiazol-2-yl)amino]-N-[2-(pyrrolidin-1-yl)ethyl]benzamide::aminothiazole analogue, 33

SMILES Brc1cnc(Nc2ccc(cc2)C(=O)NCCN2CCCC2)s1

InChI Key InChIKey=DMIBSRUIECZFKG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 25689   

TargetAurora kinase A(Human)
Novartis

LigandPNGBDBM25689(4-[(5-bromo-1,3-thiazol-2-yl)amino]-N-[2-(pyrrolid...)
Affinity DataIC50: 5.32E+3nMAssay Description:The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2008
Entry Details Article
PubMed