BDBM25680 4-[(5-bromo-1,3-thiazol-2-yl)amino]benzoic acid::aminothiazole analogue, 24

SMILES OC(=O)c1ccc(Nc2ncc(Br)s2)cc1

InChI Key InChIKey=MEBBDDHYRXPAPC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 25680   

TargetAurora kinase A(Human)
Novartis

LigandPNGBDBM25680(4-[(5-bromo-1,3-thiazol-2-yl)amino]benzoic acid | ...)
Affinity DataIC50: 79nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2008
Entry Details Article
PubMed
TargetAromatase(Human)
Novartis

LigandPNGBDBM25680(4-[(5-bromo-1,3-thiazol-2-yl)amino]benzoic acid | ...)
Affinity DataIC50: 960nMAssay Description:Enzyme activity was assayed using Z-LYTE Enzymatic Kinase Assay format (Invitrogen Corp., Carlsbad, CA) in the SelectScreen Kinase Profiling Service...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2008
Entry Details Article
PubMed
LigandPNGBDBM25680(4-[(5-bromo-1,3-thiazol-2-yl)amino]benzoic acid | ...)
Affinity DataIC50: 1.00E+4nMAssay Description:Enzyme activity was assayed using Z-LYTE Enzymatic Kinase Assay format (Invitrogen Corp., Carlsbad, CA) in the SelectScreen Kinase Profiling Service...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2008
Entry Details Article
PubMed