BDBM2568 3-(benzylsulfanyl)-4-hydroxy-6-phenyl-2H-pyran-2-one::4-hydroxy-6-phenylpyranone 16::CHEMBL14930

SMILES Oc1cc(oc(=O)c1SCc1ccccc1)-c1ccccc1

InChI Key InChIKey=QDXWWEZZGVALSV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 2568   

TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM2568(3-(benzylsulfanyl)-4-hydroxy-6-phenyl-2H-pyran-2-o...)
Affinity DataIC50: 1.70E+3nMpH: 4.7 T: 2°CAssay Description:For determination of IC50 values, HIV-1 protease was added to assay buffer containing inhibitor and the substrate (H-His-Lys-Ala-Arg-Val-Leu- (p-NO2)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM2568(3-(benzylsulfanyl)-4-hydroxy-6-phenyl-2H-pyran-2-o...)
Affinity DataIC50: 1.70E+3nMAssay Description:In vitro inhibitory activity against HIV-1 protease(PR).More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article