BDBM256686 US10053456, 65::US10414761, Example 65::US10968213, Example 65::US9487511, 65::US9718814, 65

SMILES Cc1sc(cc1C(=O)NC1CCC(F)(F)CC1)C1CC1NCC1CC1

InChI Key InChIKey=HFYHFQRFNIMQNX-UHFFFAOYSA-N

Data  18 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 256686   

TargetLysine-specific histone demethylase 1A(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 256686BDBM256686(US9487511, 65 | US10053456, 65 | US9718814, 65 | U...)
Affinity DataIC50: 100nMpH: 8.0 T: 2°CAssay Description:A test compound dissolved in DMSO was added by to a reaction solution (50 mM Tris-HCl (pH 8.0), 0.1% BSA, 1 mM DTT) containing LSD1 enzyme, and the m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2018
Entry Details
US Patent

TargetAmine oxidase [flavin-containing] A(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 256686BDBM256686(US9487511, 65 | US10053456, 65 | US9718814, 65 | U...)
Affinity DataIC50: 2.50E+4nMpH: 7.5 T: 2°CAssay Description:The MAO-A inhibitory activity evaluation described below followed the protocol of MAO-Glo (registered trademark) Assay of Promega KK.A test compound ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2018
Entry Details
US Patent

TargetAmine oxidase [flavin-containing] B(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 256686BDBM256686(US9487511, 65 | US10053456, 65 | US9718814, 65 | U...)
Affinity DataIC50: 1.00E+5nMpH: 7.5 T: 2°CAssay Description:The MAO-B inhibitory activity evaluation described below followed the protocol of MAO-Glo (registered trademark) Assay of Promega KK.A test compound ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2018
Entry Details
US Patent