BDBM256680 US10053456, 59::US10414761, Example 59::US10968213, Example 59::US9487511, 59::US9718814, 59::US9920047, 59

SMILES Cc1nnc(NC(=O)c2cc(cs2)C2CC2NC2CCN(CC2)C2CC2)s1

InChI Key InChIKey=KFMJDLZJIHKNAY-UHFFFAOYSA-N

Data  21 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 256680   

TargetLysine-specific histone demethylase 1A(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 256680BDBM256680(US9487511, 59 | US10053456, 59 | US9718814, 59 | U...)
Affinity DataIC50: 100nMpH: 8.0 T: 2°CAssay Description:A test compound dissolved in DMSO was added by to a reaction solution (50 mM Tris-HCl (pH 8.0), 0.1% BSA, 1 mM DTT) containing LSD1 enzyme, and the m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2018
Entry Details
US Patent

TargetAmine oxidase [flavin-containing] B(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 256680BDBM256680(US9487511, 59 | US10053456, 59 | US9718814, 59 | U...)
Affinity DataIC50: 1.00E+5nMpH: 7.5 T: 2°CAssay Description:The MAO-B inhibitory activity evaluation described below followed the protocol of MAO-Glo (registered trademark) Assay of Promega KK.A test compound ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2018
Entry Details
US Patent

TargetAmine oxidase [flavin-containing] A(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 256680BDBM256680(US9487511, 59 | US10053456, 59 | US9718814, 59 | U...)
Affinity DataIC50: 1.00E+5nMpH: 7.5 T: 2°CAssay Description:The MAO-A inhibitory activity evaluation described below followed the protocol of MAO-Glo (registered trademark) Assay of Promega KK.A test compound ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2018
Entry Details
US Patent