BDBM256666 BDBM256667::US9487511, 45

SMILES NC1CCC(CC1)N[C@@H]1C[C@@H]1c1cc(cs1)C(=O)NC1CCC(F)(F)CC1

InChI Key InChIKey=FWHPYDSBBQNKFD-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 256666   

LigandPNGBDBM256666(BDBM256667 | US9487511, 45)
Affinity DataIC50: 100nMpH: 8.0 T: 2°CAssay Description:A test compound dissolved in DMSO was added by to a reaction solution (50 mM Tris-HCl (pH 8.0), 0.1% BSA, 1 mM DTT) containing LSD1 enzyme, and the m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2017
Entry Details
Go to US Patent

LigandPNGBDBM256666(BDBM256667 | US9487511, 45)
Affinity DataIC50: 100nMpH: 8.0 T: 2°CAssay Description:A test compound dissolved in DMSO was added by to a reaction solution (50 mM Tris-HCl (pH 8.0), 0.1% BSA, 1 mM DTT) containing LSD1 enzyme, and the m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2017
Entry Details
Go to US Patent

TargetAmine oxidase [flavin-containing] A(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM256666(BDBM256667 | US9487511, 45)
Affinity DataIC50: 1.00E+5nMpH: 7.5 T: 2°CAssay Description:The MAO-A inhibitory activity evaluation described below followed the protocol of MAO-Glo (registered trademark) Assay of Promega KK.A test compound ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2017
Entry Details
Go to US Patent

TargetAmine oxidase [flavin-containing] A(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM256666(BDBM256667 | US9487511, 45)
Affinity DataIC50: 1.00E+5nMpH: 7.5 T: 2°CAssay Description:The MAO-A inhibitory activity evaluation described below followed the protocol of MAO-Glo (registered trademark) Assay of Promega KK.A test compound ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2017
Entry Details
Go to US Patent

TargetAmine oxidase [flavin-containing] B(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM256666(BDBM256667 | US9487511, 45)
Affinity DataIC50: 1.00E+5nMpH: 7.5 T: 2°CAssay Description:The MAO-B inhibitory activity evaluation described below followed the protocol of MAO-Glo (registered trademark) Assay of Promega KK. A test compound...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2017
Entry Details
Go to US Patent

TargetAmine oxidase [flavin-containing] B(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM256666(BDBM256667 | US9487511, 45)
Affinity DataIC50: 1.00E+5nMpH: 7.5 T: 2°CAssay Description:The MAO-B inhibitory activity evaluation described below followed the protocol of MAO-Glo (registered trademark) Assay of Promega KK. A test compound...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2017
Entry Details
Go to US Patent