BDBM256661 BDBM256662::US10053456, 41::US10414761, Example 41::US10968213, Example 41::US9487511, 40::US9718814, 41::US9920047, 41
SMILES Cc1nnc(NC(=O)c2csc(c2)C2CC2NCC2CCOCC2)s1
InChI Key InChIKey=JQXCIDIOAGEDEC-UHFFFAOYSA-N
Data 42 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 42 hits for monomerid = 256661
Affinity DataIC50: 1.00E+5nMAssay Description:MAO-B: The MAO-B inhibitory activity evaluation described below followed the protocol of MAO-Glo (registered trademark) Assay of Promega KK.A test co...More data for this Ligand-Target Pair
Affinity DataIC50: 6.70E+4nMpH: 7.5 T: 2°CAssay Description:The MAO-A inhibitory activity evaluation described below followed the protocol of MAO-Glo (registered trademark) Assay of Promega KK.A test compound ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMpH: 7.5 T: 2°CAssay Description:The MAO-B inhibitory activity evaluation described below followed the protocol of MAO-Glo (registered trademark) Assay of Promega KK.A test compound ...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:A test compound dissolved in DMSO was added by to a reaction solution (50 mM Tris-HCl (pH 8.0), 0.1% BSA, 1 mM DTT) containing LSD1 enzyme, and the m...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:A test compound dissolved in DMSO was added to a reaction solution (100 mM HEPES (pH 7.5), 5% glycerol) containing MAO-A enzyme (Sigma-Aldrich Co. LL...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:A test compound dissolved in DMSO was added to a reaction solution (100 mM HEPES (pH 7.5), 5% glycerol, 10% DMSO) containing MAO-B enzyme (Sigma-Aldr...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:A test compound dissolved in DMSO was added by to a reaction solution (50 mM Tris-HCl (pH 8.0), 0.1% BSA, 1 mM DTT) containing LSD1 enzyme, and the m...More data for this Ligand-Target Pair
Affinity DataIC50: 6.70E+4nMAssay Description:A test compound dissolved in DMSO was added to a reaction solution (100 mM HEPES (pH 7.5), 5% glycerol) containing MAO-A enzyme (Sigma-Aldrich Co. LL...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:A test compound dissolved in DMSO was added to a reaction solution (100 mM HEPES (pH 7.5), 5% glycerol, 10% DMSO) containing MAO-B enzyme (Sigma-Aldr...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:LSD1: A test compound dissolved in DMSO was added by to a reaction solution (50 mM Tris-HCl (pH 8.0), 0.1% BSA, 1 mM DTT) containing LSD1 enzyme, and...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:MAO-A: The MAO-A inhibitory activity evaluation described below followed the protocol of MAO-Glo (registered trademark) Assay of Promega KK.A test co...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMpH: 8.0 T: 2°CAssay Description:A test compound dissolved in DMSO was added by to a reaction solution (50 mM Tris-HCl (pH 8.0), 0.1% BSA, 1 mM DTT) containing LSD1 enzyme, and the m...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:LSD1: A test compound dissolved in DMSO was added by to a reaction solution (50 mM Tris-HCl (pH 8.0), 0.1% BSA, 1 mM DTT) containing LSD1 enzyme, and...More data for this Ligand-Target Pair
Affinity DataIC50: 6.70E+4nMAssay Description:MAO-A: The MAO-A inhibitory activity evaluation described below followed the protocol of MAO-Glo (registered trademark) Assay of Promega KK.A test co...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:MAO-B: The MAO-B inhibitory activity evaluation described below followed the protocol of MAO-Glo (registered trademark) Assay of Promega KK.A test co...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:LSD1: A test compound dissolved in DMSO was added by to a reaction solution (50 mM Tris-HCl (pH 8.0), 0.1% BSA, 1 mM DTT) containing LSD1 enzyme, and...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:The MAO-A inhibitory activity evaluation described below followed the protocol of MAO-Glo (registered trademark) Assay of Promega KK.A test compound ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:The MAO-B inhibitory activity evaluation described below followed the protocol of MAO-Glo (registered trademark) Assay of Promega KK.A test compound ...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:LSD1: A test compound dissolved in DMSO was added by to a reaction solution (50 mM Tris-HCl (pH 8.0), 0.1% BSA, 1 mM DTT) containing LSD1 enzyme, and...More data for this Ligand-Target Pair
Affinity DataIC50: 6.70E+4nMAssay Description:The MAO-A inhibitory activity evaluation described below followed the protocol of MAO-Glo (registered trademark) Assay of Promega KK.A test compound ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:The MAO-B inhibitory activity evaluation described below followed the protocol of MAO-Glo (registered trademark) Assay of Promega KK.A test compound ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMpH: 7.5 T: 2°CAssay Description:A test compound dissolved in DMSO was added to a reaction solution (100 mM HEPES (pH 7.5), 5% glycerol, 10% DMSO) containing MAO-B enzyme (Sigma-Aldr...More data for this Ligand-Target Pair
TargetGlutathione S-transferase P/Lysine-specific histone demethylase 1A [172-833](Human)
Takeda Pharmaceutical
US Patent
Takeda Pharmaceutical
US Patent
Affinity DataIC50: 100nMpH: 8.0 T: 2°CAssay Description:A test compound dissolved in DMSO was added by to a reaction solution (50 mM Tris-HCl (pH 8.0), 0.1% BSA, 1 mM DTT) containing LSD1 enzyme, and the m...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMpH: 7.5 T: 2°CAssay Description:The MAO-A inhibitory activity evaluation described below followed the protocol of MAO-Glo (registered trademark) Assay of Promega KK.A test compound ...More data for this Ligand-Target Pair
Affinity DataIC50: 6.70E+4nMpH: 7.5 T: 2°CAssay Description:The MAO-A inhibitory activity evaluation described below followed the protocol of MAO-Glo (registered trademark) Assay of Promega KK.A test compound ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMpH: 7.5 T: 2°CAssay Description:The MAO-B inhibitory activity evaluation described below followed the protocol of MAO-Glo (registered trademark) Assay of Promega KK. A test compound...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMpH: 7.5 T: 2°CAssay Description:The MAO-B inhibitory activity evaluation described below followed the protocol of MAO-Glo (registered trademark) Assay of Promega KK. A test compound...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMpH: 8.0 T: 2°CAssay Description:A test compound dissolved in DMSO was added by to a reaction solution (50 mM Tris-HCl (pH 8.0), 0.1% BSA, 1 mM DTT) containing LSD1 enzyme, and the m...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMpH: 7.5 T: 2°CAssay Description:A test compound dissolved in DMSO was added to a reaction solution (100 mM HEPES (pH 7.5), 5% glycerol) containing MAO-A enzyme (Sigma-Aldrich Co. LL...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMpH: 7.5 T: 2°CAssay Description:A test compound dissolved in DMSO was added to a reaction solution (100 mM HEPES (pH 7.5), 5% glycerol, 10% DMSO) containing MAO-B enzyme (Sigma-Aldr...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMpH: 8.0 T: 2°CAssay Description:A test compound dissolved in DMSO was added by to a reaction solution (50 mM Tris-HCl (pH 8.0), 0.1% BSA, 1 mM DTT) containing LSD1 enzyme, and the m...More data for this Ligand-Target Pair
Affinity DataIC50: 6.70E+4nMpH: 7.5 T: 2°CAssay Description:A test compound dissolved in DMSO was added to a reaction solution (100 mM HEPES (pH 7.5), 5% glycerol) containing MAO-A enzyme (Sigma-Aldrich Co. LL...More data for this Ligand-Target Pair
TargetGlutathione S-transferase P/Lysine-specific histone demethylase 1A [172-833](Human)
Takeda Pharmaceutical
US Patent
Takeda Pharmaceutical
US Patent
Affinity DataIC50: 100nMpH: 8.0 T: 2°CAssay Description:A test compound dissolved in DMSO was added by to a reaction solution (50 mM Tris-HCl (pH 8.0), 0.1% BSA, 1 mM DTT) containing LSD1 enzyme, and the m...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMpH: 8.0 T: 2°CAssay Description:A test compound dissolved in DMSO was added by to a reaction solution (50 mM Tris-HCl (pH 8.0), 0.1% BSA, 1 mM DTT) containing LSD1 enzyme, and the m...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMpH: 7.5 T: 2°CAssay Description:The MAO-A inhibitory activity evaluation described below followed the protocol of MAO-Glo (registered trademark) Assay of Promega KK.A test compound ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMpH: 7.5 T: 2°CAssay Description:The MAO-B inhibitory activity evaluation described below followed the protocol of MAO-Glo (registered trademark) Assay of Promega KK.A test compound ...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMpH: 8.0 T: 2°CAssay Description:A test compound dissolved in DMSO was added by to a reaction solution (50 mM Tris-HCl (pH 8.0), 0.1% BSA, 1 mM DTT) containing LSD1 enzyme, and the m...More data for this Ligand-Target Pair
Affinity DataIC50: 6.70E+4nMpH: 7.5 T: 2°CAssay Description:The MAO-A inhibitory activity evaluation described below followed the protocol of MAO-Glo (registered trademark) Assay of Promega KK.A test compound ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMpH: 7.5 T: 2°CAssay Description:The MAO-B inhibitory activity evaluation described below followed the protocol of MAO-Glo (registered trademark) Assay of Promega KK.A test compound ...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMpH: 8.0 T: 2°CAssay Description:A test compound dissolved in DMSO was added by to a reaction solution (50 mM Tris-HCl (pH 8.0), 0.1% BSA, 1 mM DTT) containing LSD1 enzyme, and the m...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMpH: 7.5 T: 2°CAssay Description:The MAO-A inhibitory activity evaluation described below followed the protocol of MAO-Glo (registered trademark) Assay of Promega KK.A test compound ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMpH: 7.5 T: 2°CAssay Description:The MAO-B inhibitory activity evaluation described below followed the protocol of MAO-Glo (registered trademark) Assay of Promega KK.A test compound ...More data for this Ligand-Target Pair