BDBM25653 4-(4-{2H,4H-indeno[1,2-c]pyrazol-6-yl}-1-methyl-1H-pyrazol-3-yl)pyridine::pyrazole-based inhibitor, 35

SMILES Cn1cc(c(n1)-c1ccncc1)-c1ccc-2c(Cc3c[nH]nc-23)c1

InChI Key InChIKey=MAOYHJWWEYWDEQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 25653   

TargetSerine/threonine-protein kinase B-raf(Human)
Array Biopharma

LigandPNGBDBM25653(4-(4-{2H,4H-indeno[1,2-c]pyrazol-6-yl}-1-methyl-1H...)
Affinity DataIC50: 1.5nMAssay Description:Activity of human recombinant B-Raf protein was assessed in vitro by assay of the incorporation of radiolabeled phosphate to recombinant MAP kinase (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2008
Entry Details Article
PubMed