BDBM2564 2-(3,4-dihydroxy-5-oxo-2,5-dihydrofuran-2-yl)-2-hydroxyethyl 5-cyclohexylpentanoate::Parke-Davis compound 7

SMILES OC(COC(=O)CCCCC1CCCCC1)C1OC(=O)C(O)C1=O

InChI Key InChIKey=LFDGQBHODLGSBR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 2564   

TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM2564(2-(3,4-dihydroxy-5-oxo-2,5-dihydrofuran-2-yl)-2-hy...)
Affinity DataIC50: 2.90E+4nMpH: 4.7 T: 2°CAssay Description:For determination of IC50 values, HIV-1 protease was added to assay buffer containing inhibitor and the substrate (H-His-Lys-Ala-Arg-Val-Leu- (p-NO2)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2004
Entry Details Article
PubMed