BDBM256125 US9487462, 6

SMILES OC(=O)c1csc(CN(CC(c2ccccc2)c2ccccc2)Cc2ccc(OCc3ccccc3)cc2)n1

InChI Key InChIKey=WFWWEVFFBYLNLW-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 256125   

Target72 kDa type IV collagenase(Human)
Pharmahungary 2000

US Patent
LigandPNGBDBM256125(US9487462, 6)
Affinity DataIC50: 2.60E+4nMpH: 7.5 T: 2°CAssay Description:Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2017
Entry Details
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TargetMatrix metalloproteinase-9(Human)
Pharmahungary 2000

US Patent
LigandPNGBDBM256125(US9487462, 6)
Affinity DataIC50: 1.00E+4nMpH: 7.5 T: 2°CAssay Description:Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2017
Entry Details
Go to US Patent

TargetCollagenase 3(Human)
Pharmahungary 2000

US Patent
LigandPNGBDBM256125(US9487462, 6)
Affinity DataIC50: 1.76E+3nMpH: 7.5 T: 2°CAssay Description:Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2017
Entry Details
Go to US Patent

TargetInterstitial collagenase(Human)
Pharmahungary 2000

US Patent
LigandPNGBDBM256125(US9487462, 6)
Affinity DataIC50: 2.60E+4nMpH: 7.5 T: 2°CAssay Description:Stock solution of substrate (Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) was prepared in DMSO at a concentration of 6 mM. Assays were performed in an as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2017
Entry Details
Go to US Patent