BDBM255848 5-(3-{1-[4-amino-3-(5-cyanopyridin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]ethyl}-5-chloro-2-ethoxy-6-methylphenyl)-N,N-dimethylpyridine-2-carboxamide tris(trifluoroacetate)::US9707233, 57

SMILES CCOc1c(cc(Cl)c(C)c1-c1ccc(nc1)C(=O)N(C)C)C(C)n1nc(-c2cc(ccn2)C#N)c2c(N)ncnc12

InChI Key InChIKey=DETNQALWBUXAOP-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 255848   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta/delta isoform(Human)
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US Patent

LigandBDBM255848(5-(3-{1-[4-amino-3-(5-cyanopyridin-3-yl)-1H-pyrazo...)Copy SMILESCopy InChI

Affinity DataIC50: 10nMpH: 6.7 T: 2°CAssay Description:Lipid kinase substrate, phosphoinositol-4,5-bisphosphate (PIP2), are purchased from Echelon Biosciences (Salt Lake City, Utah). PI3K isoforms α,...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
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Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
10/30/2018
Entry Details
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