BDBM25559 4-arylamino-3-pyridinecarbonitrile, 4q::5-(3,4-dimethoxyphenyl)-4-(1H-indol-6-ylamino)pyridine-3-carbonitrile::BMCL192461 Compound 1b::CHEMBL492252

SMILES COc1ccc(cc1OC)-c1cncc(C#N)c1Nc1ccc2cc[nH]c2c1

InChI Key InChIKey=UXKAONQBOGJYCN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 25559   

TargetProtein kinase C theta type(Human)
Wyeth Research

LigandPNGBDBM25559(CHEMBL492252 | 5-(3,4-dimethoxyphenyl)-4-(1H-indol...)
Affinity DataIC50: 2.20E+3nMpH: 7.2 T: 2°CAssay Description:All IC50s were measured by using a modified IMAP protocol from Molecular Devices. The kinase reaction was carried out in a Corning Costar 384 well pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2008
Entry Details Article
PubMed
TargetProtein kinase C theta type(Human)
Wyeth Research

LigandPNGBDBM25559(CHEMBL492252 | 5-(3,4-dimethoxyphenyl)-4-(1H-indol...)
Affinity DataIC50: 2.20E+3nMpH: 7.2 T: 2°CAssay Description:All IC50s were measured by using a modified IMAP protocol from Molecular Devices. The kinase reaction was carried out in a Corning Costar 384 well pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2009
Entry Details Article
PubMed
TargetProtein kinase C theta type(Human)
Wyeth Research

LigandPNGBDBM25559(CHEMBL492252 | 5-(3,4-dimethoxyphenyl)-4-(1H-indol...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human PKCtheta by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed