BDBM25549 4-[(4-chlorophenyl)amino]-5-(3,4-dimethoxyphenyl)pyridine-3-carbonitrile::4-arylamino-3-pyridinecarbonitrile, 4g

SMILES COc1ccc(cc1OC)-c1cncc(C#N)c1Nc1ccc(Cl)cc1

InChI Key InChIKey=XBRSPOIYHCTXLY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 25549   

TargetProtein kinase C theta type(Human)
Wyeth Research

LigandPNGBDBM25549(4-[(4-chlorophenyl)amino]-5-(3,4-dimethoxyphenyl)p...)
Affinity DataIC50: 2.80E+3nMpH: 7.2 T: 2°CAssay Description:All IC50s were measured by using a modified IMAP protocol from Molecular Devices. The kinase reaction was carried out in a Corning Costar 384 well pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2008
Entry Details Article
PubMed
TargetProtein kinase C theta type(Human)
Wyeth Research

LigandPNGBDBM25549(4-[(4-chlorophenyl)amino]-5-(3,4-dimethoxyphenyl)p...)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of full length human PKCtheta using 5-FAM-RFARKGSLRQKNV-OH peptide substrate incubated for 30 mins by IMAP kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed