BDBM25537 4-(2-hydroxyethyl)-8-methyl-12,14-dioxa-8-azatetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-1(10),2(7),3,5,8,11(15),16-heptaen-8-ium chloride::sanguinarine analogue, 35

SMILES C[n+]1cc2c3OCOc3ccc2c2cc(CCO)ccc12

InChI Key InChIKey=IAUBUNZOEUZEQX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 25537   

TargetBcl-2-like protein 1(Human)
A* Star

LigandPNGBDBM25537(4-(2-hydroxyethyl)-8-methyl-12,14-dioxa-8-azatetra...)
Affinity DataIC50: 3.00E+3nMpH: 8.0 T: 2°CAssay Description:In the fluorescence polarization assay, the Bcl-XL protein is incubated with a fluorescein-tagged Bak-BH3 peptide. The Bcl-XL:Bak-BH3 peptide complex...More data for this Ligand-Target Pair
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Date in BDB:
11/22/2008
Entry Details Article
PubMed