BDBM25505 1-(3-methoxyphenyl)-3-methyl-N-[(1S)-1-phenylethyl]-1H-pyrazolo[4,3-c]pyridin-6-amine::2-amino-pyrazolopyridine, 10

SMILES COc1cccc(c1)-n1nc(C)c2cnc(N[C@@H](C)c3ccccc3)cc12

InChI Key InChIKey=AVCWXYCDBRFSPG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 25505   

TargetSerine/threonine-protein kinase PLK1(Human)
Sunesis Pharmaceuticals

LigandPNGBDBM25505(1-(3-methoxyphenyl)-3-methyl-N-[(1S)-1-phenylethyl...)
Affinity DataIC50: 5.93E+3nMpH: 7.2 T: 2°CAssay Description:An IMAP fluorescence polarization-based assay format (Molecular Devices) was used to determine the ability of compounds to inhibit the phosphorylatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2008
Entry Details Article
PubMed