BDBM25497 4-(4-chloro-2-fluorophenyl)-2-(2-chloropyridin-4-yl)-6-methyl-N-(3-methyl-1H-indazol-5-yl)-1,4-dihydropyrimidine-5-carboxamide::Dihydropyrimidine, 26

SMILES Cc1n[nH]c2ccc(NC(=O)C3=C(C)N=C(NC3c3ccc(Cl)cc3F)c3ccnc(Cl)c3)cc12

InChI Key InChIKey=VLMQNCCSDWVDDD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 25497   

LigandPNGBDBM25497(4-(4-chloro-2-fluorophenyl)-2-(2-chloropyridin-4-y...)
Affinity DataIC50: 15nMpH: 7.4 T: 2°CAssay Description:The assay of Rock-1 activity involved incubation with peptide substrate and ATP33, and the incorporation of P33 into the peptide was quantified by Sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2008
Entry Details Article
PubMed