BDBM254934 US9499542, 17::US9675594, 17

SMILES N#Cc1c[nH]c2nc(Nc3ccccn3)cc(-c3ccccc3)c12

InChI Key InChIKey=BBKNRIAOOMXTKD-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 254934   

LigandPNGBDBM254934(US9675594, 17 | US9499542, 17)
Affinity DataIC50: 527nMpH: 8.5 T: 2°CAssay Description:LRRK2 kinase activity is measured using a LanthaScreen kinase activity assay available from Invitrogen (Life Technologies Corporation). The assay is ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
Go to US Patent

LigandPNGBDBM254934(US9675594, 17 | US9499542, 17)
Affinity DataIC50: 340nMpH: 8.5 T: 2°CAssay Description:LRRK2 kinase activity is measured using a LanthaScreen kinase activity assay available from Invitrogen (Life Technologies Corporation). The assay is ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
Go to US Patent

LigandPNGBDBM254934(US9675594, 17 | US9499542, 17)
Affinity DataEC50:  527nMAssay Description:In the assay, 1 nM LRRK2 WT or 250 pM LRRK2 G2019S kinase is incubated with the test compound (typically at 0 to 30 μM) for 30 minutes before th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2018
Entry Details
Go to US Patent

LigandPNGBDBM254934(US9675594, 17 | US9499542, 17)
Affinity DataEC50:  340nMAssay Description:In the assay, 1 nM LRRK2 WT or 250 pM LRRK2 G2019S kinase is incubated with the test compound (typically at 0 to 30 μM) for 30 minutes before th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2018
Entry Details
Go to US Patent