BDBM254498 US9468661, 109::US9468661, 76

SMILES CC1[C@@H](CNC(=O)[C@@H]2C[C@H]3C[C@H]3N2C(=O)Cn2nc(C(C)=O)c3cc(OCc4ncccn4)ccc23)C1(Cl)Cl

InChI Key InChIKey=JCKWSCOGPWSJDQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 254498   

TargetComplement factor D(Human)
Novartis

US Patent
LigandPNGBDBM254498(US9468661, 76 | US9468661, 109)
Affinity DataIC50: 3nMpH: 7.5 T: 2°CAssay Description:Method 1: Recombinant human factor D (expressed in E. coli and purified using standard methods) at 10 nM concentration is incubated with test compoun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
Go to US Patent

TargetComplement factor D(Human)
Novartis

US Patent
LigandPNGBDBM254498(US9468661, 76 | US9468661, 109)
Affinity DataIC50: 49nMpH: 7.5 T: 2°CAssay Description:Method 1: Recombinant human factor D (expressed in E. coli and purified using standard methods) at 10 nM concentration is incubated with test compoun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
Go to US Patent