BDBM25421 2-(2,4-dichlorophenoxy)-5-(3-phenylpropyl)phenol::Triclosan derivative, 22

SMILES c1ccc(cc1)CCCc2ccc(c(c2)O)Oc3ccc(cc3Cl)Cl

InChI Key InChIKey=MJRPBNSOVIMDHN-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 25421   

TargetEnoyl-ACP reductase(malaria parasite P. falciparum)
Jacobus Pharmaceutical

LigandPNGBDBM25421(2-(2,4-dichlorophenoxy)-5-(3-phenylpropyl)phenol |...)
Affinity DataIC50: 440nMpH: 7.9 T: 2°CAssay Description:PfENR inhibition assays were carried out on a Cary 100 Bio Spectrophotometer or POLARstar Optima by monitoring oxidation of NADH at 340 nm. The IC50 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2008
Entry Details Article
PubMedPDB3D3D Structure (crystal)