BDBM25287 CHEMBL235690::bisphosphonate, 37::hydrogen {2-[methyl(octyl)sulfanylium]-1-phosphonoethyl}phosphonate

SMILES CCCCCCCC[S+](C)CC(P(O)(O)=O)P(O)([O-])=O

InChI Key InChIKey=HJUIIHFOXRYVDU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 25287   

TargetGeranylgeranyl pyrophosphate synthase(Human)
National Taiwan University

LigandPNGBDBM25287(hydrogen {2-[methyl(octyl)sulfanylium]-1-phosphono...)
Affinity DataIC50: 3.24E+3nMAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed
TargetFarnesyl pyrophosphate synthase(Human)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM25287(hydrogen {2-[methyl(octyl)sulfanylium]-1-phosphono...)
Affinity DataIC50: 360nMAssay Description:Inhibition of human FPPSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed