BDBM25272 CHEMBL238046::bisphosphonate, 25::hydrogen {2-[dodecyl(methyl)sulfanylium]-1-phosphonoethyl}phosphonate

SMILES CCCCCCCCCCCC[S+](C)CC(P(O)(O)=O)P(O)([O-])=O

InChI Key InChIKey=NYXTVKKWHZOSOD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 25272   

TargetGeranylgeranyl pyrophosphate synthase(Human)
National Taiwan University

LigandPNGBDBM25272(hydrogen {2-[dodecyl(methyl)sulfanylium]-1-phospho...)
Affinity DataIC50: 1.23E+3nMpH: 7.0 T: 2°CAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed
TargetFarnesyl pyrophosphate synthase(Human)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM25272(hydrogen {2-[dodecyl(methyl)sulfanylium]-1-phospho...)
Affinity DataIC50: 260nMAssay Description:Inhibition of human FPPSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed