BDBM25265 (1-hydroxy-1-phosphonononyl)phosphonic acid::CHEMBL110971::bisphosphonate, 4

SMILES CCCCCCCCC(O)(P(=O)(O)O)P(=O)(O)O

InChI Key InChIKey=COHUUYPEYRMWTH-UHFFFAOYSA-N

Data  1 KI  4 IC50

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 25265   

TargetGeranylgeranyl pyrophosphate synthase(Human)
National Taiwan University

LigandPNGBDBM25265((1-hydroxy-1-phosphonononyl)phosphonic acid | CHEM...)
Affinity DataIC50: 710nMpH: 7.0 T: 2°CAssay Description:The inhibitory activity of each test compound was evaluated by monitoring the formation of [14C]GGPP from FPP, using [14C]IPP as the substrate. To co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed
TargetH(+)-exporting diphosphatase(Trypanosoma brucei)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM25265((1-hydroxy-1-phosphonononyl)phosphonic acid | CHEM...)
Affinity DataIC50: 4.77E+4nMAssay Description:Inhibition of recombinant Trypanosoma brucei soluble vacuolar pyrophosphatase expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetFarnesyl pyrophosphate synthase(Human)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM25265((1-hydroxy-1-phosphonononyl)phosphonic acid | CHEM...)
Affinity DataIC50: 4.54E+3nMAssay Description:Inhibitory concentration against Trypanosoma brucei farnesyl pyrophosphate synthase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFarnesyl pyrophosphate synthase(Human)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM25265((1-hydroxy-1-phosphonononyl)phosphonic acid | CHEM...)
Affinity DataIC50: 8.45E+3nMAssay Description:Inhibition of Trypanosoma cruzi farnesyl pyrophosphate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFarnesyl pyrophosphate synthase(Human)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM25265((1-hydroxy-1-phosphonononyl)phosphonic acid | CHEM...)
Affinity DataKi:  590nMAssay Description:Binding affinity towards Trypanosoma cruzi farnesyl pyrophosphate synthase (TcFPPS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed