BDBM25206 2,4-Pyrimidine derivative, 8::4-N-(5-chloro-2H-1,3-benzodioxol-4-yl)-2-N-phenylpyrimidine-2,4-diamine

SMILES Clc1ccc2OCOc2c1Nc1ccnc(Nc2ccccc2)n1

InChI Key InChIKey=BPBBEBGGGQEHFN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 25206   

TargetEphrin type-B receptor 4(Human)
Astrazeneca

LigandPNGBDBM25206(4-N-(5-chloro-2H-1,3-benzodioxol-4-yl)-2-N-phenylp...)
Affinity DataIC50: 1.55E+3nMpH: 7.4 T: 2°CAssay Description:This assay detects inhibitors of EphB4-mediated phosphorylation of a polypeptide substrate using Alphascreen luminescence detection technology. The r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed