BDBM25204 4,6-Pyrimidine derivative, 6::4-N-(5-chloro-2H-1,3-benzodioxol-4-yl)-6-N-(3,4,5-trimethoxyphenyl)pyrimidine-4,6-diamine

SMILES COc1cc(Nc2cc(Nc3c4OCOc4ccc3Cl)ncn2)cc(OC)c1OC

InChI Key InChIKey=FPAJVRNSPYYJKR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 25204   

TargetEphrin type-B receptor 4(Human)
Astrazeneca

LigandPNGBDBM25204(4-N-(5-chloro-2H-1,3-benzodioxol-4-yl)-6-N-(3,4,5-...)
Affinity DataIC50: 2.54E+3nMpH: 7.4 T: 2°CAssay Description:This assay detects inhibitors of EphB4-mediated phosphorylation of a polypeptide substrate using Alphascreen luminescence detection technology. The r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed