BDBM25197 6-substituted 4-anilinoquinoline, 37::N-(cyclopropylmethyl)-4-[(5-hydroxy-2-methylphenyl)amino]quinoline-6-sulfonamide

SMILES Cc1ccc(O)cc1Nc1ccnc2ccc(cc12)S(=O)(=O)NCC1CC1

InChI Key InChIKey=FNXPJCFHZYAHIZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 25197   

LigandPNGBDBM25197(N-(cyclopropylmethyl)-4-[(5-hydroxy-2-methylphenyl...)
Affinity DataIC50: 90nMpH: 7.4 T: 2°CAssay Description:The biochemical activity of compound was determined by incubation with Ret kinase and the substrate in the presence of ATP/ [gamma-33P] ATP. After in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2008
Entry Details Article
PubMed