BDBM251897 US9475809, 9::US9918969, 9

SMILES Clc1ccc(Br)c(c1)-c1cc(=O)n(CC(=O)Nc2ccc(cc2)-c2nnn[nH]2)c2CCC(=O)c12

InChI Key InChIKey=LHYUYAZVUPBAGD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 251897   

TargetCoagulation factor XI(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM251897(US9475809, 9 | US9918969, 9)
Affinity DataIC50: 170nMpH: 7.4 T: 2°CAssay Description:The factor XIa inhibition of the inventive substances is determined using a biochemical test system which utilizes the reaction of a peptidic factor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
Go to US Patent

TargetCoagulation factor XI(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM251897(US9475809, 9 | US9918969, 9)
Affinity DataIC50: 170nMAssay Description:The factor XIa inhibition of the inventive substances is determined using a biochemical test system which utilizes the reaction of a peptidic factor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/4/2020
Entry Details
Go to US Patent