BDBM2510 (+/-)-3-[ 1-(Cyclopentylthio)-3-methylbutyl]-4-hydroxy-6-phenyl-2H-pyran-2-one::3-[1-(cyclopentylsulfanyl)-3-methylbutyl]-4-hydroxy-6-phenyl-2H-pyran-2-one::C-3-substituted Pyran-2-one 19

SMILES CC(C)CC(SC1CCCC1)c1c(O)cc(oc1=O)-c1ccccc1

InChI Key InChIKey=HIJDADBORWRDJP-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 2510   

TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM2510((+/-)-3-[ 1-(Cyclopentylthio)-3-methylbutyl]-4-hyd...)
Affinity DataKi:  33nM ΔG°:  -10.6kcal/mole IC50: 58nMpH: 4.7 T: 2°CAssay Description:For determination of IC50 values, HIV-1 protease was added to assay buffer containing inhibitor and the substrate (H-His-Lys-Ala-Arg-Val-Leu- (p-NO2)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2004
Entry Details Article
PubMed