BDBM250646 US9447148, 9.14

SMILES NC(=N)NCCC[C@@H]1NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2c[nH]cn2)NC(=O)CCC(=O)NCC[C@H](NC1=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O

InChI Key InChIKey=RWGKKLXVIVGNQZ-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 250646   

TargetMelanocyte-stimulating hormone receptor(Human)
Palatin Technologies

US Patent
LigandPNGBDBM250646(US9447148, 9.14)
Affinity DataEC50:  31nMpH: 7.5 T: 2°CAssay Description:Accumulation of intracellular cAMP was examined as a measure of the ability of the peptides of the present invention to elicit a functional response ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
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TargetMelanocyte-stimulating hormone receptor(Human)
Palatin Technologies

US Patent
LigandPNGBDBM250646(US9447148, 9.14)
Affinity DataKi:  310nM ΔG°:  -9.23kcal/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMCR-1a or hMCR-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
Go to US Patent

TargetMelanocortin receptor 4(Human)
Palatin Technologies

US Patent
LigandPNGBDBM250646(US9447148, 9.14)
Affinity DataKi:  1.00E+4nM ΔG°:  -7.09kcal/molepH: 7.5 T: 2°CAssay Description:A competitive inhibition binding assay was performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMCR-1a or hMCR-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
Go to US Patent