BDBM2500 (+/-)-4-Hydroxy-6-phenyl-3-[phenyl[(phenylmethyl)thio]methyl-2H-pyran-2-one::3-[(benzylsulfanyl)(phenyl)methyl]-4-hydroxy-6-phenyl-2H-pyran-2-one::4-hydroxy-6-phenyl-pyranylthiomethane 26::C-3-substituted Pyran-2-one 9

SMILES Oc1cc(oc(=O)c1C(SCc1ccccc1)c1ccccc1)-c1ccccc1

InChI Key InChIKey=QSFOQTCPGNVRSL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 2500   

TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM2500(3-[(benzylsulfanyl)(phenyl)methyl]-4-hydroxy-6-phe...)
Affinity DataIC50: 480nMpH: 4.7 T: 2°CAssay Description:For determination of IC50 values, HIV-1 protease was added to assay buffer containing inhibitor and the substrate (H-His-Lys-Ala-Arg-Val-Leu- (p-NO2)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM2500(3-[(benzylsulfanyl)(phenyl)methyl]-4-hydroxy-6-phe...)
Affinity DataIC50: 480nMpH: 4.7 T: 2°CAssay Description:For determination of IC50 values, HIV-1 protease was added to assay buffer containing inhibitor and the substrate (H-His-Lys-Ala-Arg-Val-Leu- (p-NO2)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2004
Entry Details Article
PubMed