BDBM249585 US9447038, 13

SMILES OC(=O)C[C@H](N(CC1CC1)Cc1ccc(OCCN2C(=O)CCC2=O)c(F)c1)c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=MRYPFKGCZCOPFK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 249585   

TargetC-X-C motif chemokine 10(Human)
Sanofi

US Patent
LigandPNGBDBM249585(US9447038, 13)
Affinity DataIC50: 97nMT: 2°CAssay Description:The composition of the binding assay buffer is determined in a course of detailed optimization procedure. This resulted in a binding assay buffer con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2017
Entry Details
Go to US Patent

TargetC-X-C chemokine receptor type 3(Human)
Sanofi

Curated by ChEMBL
LigandPNGBDBM249585(US9447038, 13)
Affinity DataIC50: 97nMAssay Description:Displacement of [125I]-CXCL10 from human recombinant CXCR3 transfected in Flp-In-CHO cell membranes after 60 mins by gamma counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2018
Entry Details Article
PubMed