BDBM2484 1-(benzenesulfonyl)-2-nitrobenzene::2-nitrophenyl phenyl sulfone (NPPS)::2NO2Ph-SO2-Ph

SMILES [O-][N+](=O)c1ccccc1S(=O)(=O)c1ccccc1

InChI Key InChIKey=GKNMUCPEXSCGKC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 2484   

TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Glaxosmithkline

LigandPNGBDBM2484(1-(benzenesulfonyl)-2-nitrobenzene | 2NO2Ph-SO2-Ph...)
Affinity DataIC50: 1.60E+4nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Glaxosmithkline

LigandPNGBDBM2484(1-(benzenesulfonyl)-2-nitrobenzene | 2NO2Ph-SO2-Ph...)
Affinity DataIC50: 5.05E+4nMpH: 7.9 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2004
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM2484(1-(benzenesulfonyl)-2-nitrobenzene | 2NO2Ph-SO2-Ph...)
Affinity DataIC50: 1.58E+4nMAssay Description:Inhibitory concentration against Reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed