BDBM248153 CA standard inhibitor, 12

SMILES CNCCNCc1cc(ccc1O)C(=O)\C=C\c1ccccn1

InChI Key InChIKey=XDVQGQMUOOVYGD-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 248153   

TargetCarbonic anhydrase 1(Human)
Ataturk University

LigandPNGBDBM248153(CA standard inhibitor, 12)
Affinity DataKi:  2.01E+3nM ΔG°:  -7.77kcal/molepH: 7.4 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalyzed CO2 hydration activity [Khalifah et al., J. Biol. Chem., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Ataturk University

LigandPNGBDBM248153(CA standard inhibitor, 12)
Affinity DataKi:  4.77E+4nM ΔG°:  -5.89kcal/molepH: 7.4 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalyzed CO2 hydration activity [Khalifah et al., J. Biol. Chem., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase(Baker's yeast)
Ataturk University

LigandPNGBDBM248153(CA standard inhibitor, 12)
Affinity DataKi:  7.95E+4nM ΔG°:  -5.59kcal/molepH: 7.4 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalyzed CO2 hydration activity [Khalifah et al., J. Biol. Chem., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2017
Entry Details Article
PubMed