BDBM248025 US9434724, 45

SMILES Cc1ccc2c(c[nH]c2c1)C(=O)OCC12CCN(CC1)CC2

InChI Key InChIKey=XVPCGPJMWAMATB-UHFFFAOYSA-N

Data  1 KI  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 248025   

TargetCytochrome P450 3A4(Human)
Alpharmagen

US Patent
LigandPNGBDBM248025(US9434724, 45)
Affinity DataIC50: 1.00E+4nMT: 2°CAssay Description:Protocol 1: Studies were carried out in human liver microsomes. Human liver microsomes were purchased from BD Gentest. DMSO stocks were prepared for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2017
Entry Details
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TargetCytochrome P450 3A4(Human)
Alpharmagen

US Patent
LigandPNGBDBM248025(US9434724, 45)
Affinity DataIC50: 1.00E+4nMT: 2°CAssay Description:Protocol 1: Studies were carried out in human liver microsomes. Human liver microsomes were purchased from BD Gentest. DMSO stocks were prepared for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2017
Entry Details
Go to US Patent

TargetCytochrome P450 2D6(Human)
Alpharmagen

US Patent
LigandPNGBDBM248025(US9434724, 45)
Affinity DataIC50: 1.00E+4nMT: 2°CAssay Description:Protocol 1: Studies were carried out in human liver microsomes. Human liver microsomes were purchased from BD Gentest. DMSO stocks were prepared for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2017
Entry Details
Go to US Patent

TargetCytochrome P450 1A2(Human)
Alpharmagen

US Patent
LigandPNGBDBM248025(US9434724, 45)
Affinity DataIC50: 1.00E+4nMT: 2°CAssay Description:Protocol 1: Studies were carried out in human liver microsomes. Human liver microsomes were purchased from BD Gentest. DMSO stocks were prepared for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2017
Entry Details
Go to US Patent

TargetCytochrome P450 2C9(Human)
Alpharmagen

US Patent
LigandPNGBDBM248025(US9434724, 45)
Affinity DataIC50: 1.00E+4nMT: 2°CAssay Description:Protocol 1: Studies were carried out in human liver microsomes. Human liver microsomes were purchased from BD Gentest. DMSO stocks were prepared for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2017
Entry Details
Go to US Patent

TargetCytochrome P450 2C19(Human)
Alpharmagen

US Patent
LigandPNGBDBM248025(US9434724, 45)
Affinity DataIC50: 1.00E+4nMT: 2°CAssay Description:Protocol 1: Studies were carried out in human liver microsomes. Human liver microsomes were purchased from BD Gentest. DMSO stocks were prepared for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2017
Entry Details
Go to US Patent

TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Alpharmagen

US Patent
LigandPNGBDBM248025(US9434724, 45)
Affinity DataKi:  63.1nM ΔG°:  -10.2kcal/mole IC50: 73.6nMpH: 7.4 T: 2°CAssay Description:Protocol 1: The assay was conducted following the literature reference Meyer E. M., et al., Analysis of 3-(4-Hydroxy, 2-Methoxybenzylidene) Anabasein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2017
Entry Details
Go to US Patent