BDBM2479 7-methyl-17-[2-(piperidin-1-yl)ethyl]-6,7,14,17-tetraazatetracyclo[12.4.0.0^{2,6}.0^{8,13}]octadeca-2,4,8(13),9,11-pentaene-15,18-dione::Pyrrolobenzothiadiazepine (PBTD) 16d

SMILES Cn1c2ccccc2n2C(=O)CN(CCN3CCCCC3)C(O)=c2c2cccn12

InChI Key InChIKey=ZQNLPBGSOGWROV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 2479   

TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Sapienza University of Rome

LigandPNGBDBM2479(7-methyl-17-[2-(piperidin-1-yl)ethyl]-6,7,14,17-te...)
Affinity DataIC50: 1.00E+5nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2004
Entry Details Article
PubMed