BDBM24775 2-methoxy-1,4-dihydronaphthalene-1,4-dione::2-methoxy-1,4-dihydronaphthalene-1,4-dione (5c)::2-methoxy-1,4-naphthoquinone, 2::CHEMBL106562

SMILES COC1=CC(=O)c2ccccc2C1=O

InChI Key InChIKey=OBGBGHKYJAOXRR-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 24775   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Bryn Mawr College

LigandPNGBDBM24775(CHEMBL106562 | 2-methoxy-1,4-dihydronaphthalene-1,...)
Affinity DataIC50: 720nMpH: 6.5 T: 2°CAssay Description:The IC50 inhibition assays were performed in a 96-well microtiter plate format using purified recombinant IDO, which was added to the substrate, L-tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2008
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
North-West University

LigandPNGBDBM24775(CHEMBL106562 | 2-methoxy-1,4-dihydronaphthalene-1,...)
Affinity DataIC50: 2.04E+4nMAssay Description:The protocol for measuring IC50 values for the inhibition of MAO-A and MAO-B has been reported in detail in a recent publication (26). The recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2016
Entry Details Article
PubMed
TargetAmine oxidase(Human)
North-West University

LigandPNGBDBM24775(CHEMBL106562 | 2-methoxy-1,4-dihydronaphthalene-1,...)
Affinity DataIC50: 2.48E+4nMAssay Description:The protocol for measuring IC50 values for the inhibition of MAO-A and MAO-B has been reported in detail in a recent publication (26). The recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2016
Entry Details Article
PubMed
TargetGenome polyprotein(Human rhinovirus B)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM24775(CHEMBL106562 | 2-methoxy-1,4-dihydronaphthalene-1,...)
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibitory activity against HRV 3Cpro using HPLC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 2(Human)
Montana State University

Curated by ChEMBL
LigandPNGBDBM24775(CHEMBL106562 | 2-methoxy-1,4-dihydronaphthalene-1,...)
Affinity DataIC50: 4.68E+4nMAssay Description:Inhibition of recombinant Cdc25B (unknown origin) using OMFP as substrate measured every 30 sec for 10 mins by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 1(Human)
Montana State University

Curated by ChEMBL
LigandPNGBDBM24775(CHEMBL106562 | 2-methoxy-1,4-dihydronaphthalene-1,...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of recombinant Cdc25A (unknown origin) using OMFP as substrate measured every 30 sec for 10 mins by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase SETD7(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM24775(CHEMBL106562 | 2-methoxy-1,4-dihydronaphthalene-1,...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of SET7 (unknown origin) using biotinylated histone polypeptide as substrate in presence of SAM by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed