BDBM24761 N-[(5-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]-3-fluorophenyl}-1-methyl-6-oxo-1,6-dihydropyrimidin-2-yl)(phenyl)methyl]propanamide::pyrimidone, 39

SMILES CCC(=O)NC(c1ccccc1)c1ncc(-c2ccc(Oc3ccnc4cc(OC)c(OC)cc34)c(F)c2)c(=O)n1C

InChI Key InChIKey=GXVVHBLXRQHBSX-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 24761   

LigandPNGBDBM24761(N-[(5-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]-3-fluor...)
Affinity DataKi:  71nM ΔG°:  -9.65kcal/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assays were done to establish IC50 values against recombinant enzymes using homogeneous time-resolved fluorescence (HTRF) assay. For ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2008
Entry Details Article
PubMed
LigandPNGBDBM24761(N-[(5-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]-3-fluor...)
Affinity DataIC50: 71nMAssay Description:Inhibition of human c-METMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed