BDBM247404 US9452985, THK-5122

SMILES CCN(CC)c1ccc(cc1)-c1ccc2cc(OCC(O)CF)ccc2n1

InChI Key InChIKey=UJKGDGDFGOYPIL-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 247404   

TargetMicrotubule-associated protein tau(Human)
Ge Healthcare

US Patent
LigandPNGBDBM247404(US9452985, THK-5122)
Affinity DataKi:  34.9nM ΔG°:  -10.2kcal/moleT: 2°CAssay Description:For tau imaging probes other than THK-5105, binding to K18-ΔK280 aggregates was evaluated with a competitive binding test using [18F] THK-5105 a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2017
Entry Details
Go to US Patent