BDBM247345 US9447091, 133

SMILES CCS(=O)(=O)Nc1cc(cc(c1)-n1cnc2cc(cnc12)-c1cnn(C)c1)-c1ccc(F)cc1F

InChI Key InChIKey=GKCYQJWFNCHFGV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 247345   

TargetFibroblast growth factor receptor 1(Human)
Orion

US Patent
LigandPNGBDBM247345(US9447091, 133)
Affinity DataIC50: 14nMAssay Description:Compounds were screened in the TR-FRET assay with FGFR1 kinase. 5 ng of FGFR1 [Upstate, USA] kinase was used for assay. The compound was incubated wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2017
Entry Details
Go to US Patent