BDBM247283 US9447085, 5

SMILES CO\N=C(\Nc1ccc(F)c(c1)[C@]1(C)CS(=O)(=O)N(C)C(=N)N1)c1ccc(OC)cn1

InChI Key InChIKey=VQGLZCUJHDZRDR-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 247283   

TargetBeta-secretase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM247283(US9447085, 5)
Affinity DataKi:  1.45E+3nM ΔG°:  -8.09kcal/molepH: 5.0 T: 2°CAssay Description:Inhibitor compounds, prepared at 3× the desired final concentration in 1×BACE assay buffer (20 mM sodium acetate pH 5.0, 10% glycerol, 0....More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2017
Entry Details
Go to US Patent