BDBM247220 US10513524, Compound (P2)::US9434733, 2-[[3-(3-pyridyloxy)azetidin-1-yl]methyl]-7-tetrahydropyran-4-yl-3H-imidazo[5,1-f][1,2,4]triazin-4-one::US9533992, 2-[[3-(3-pyridyloxy)azetidin-1-yl]methyl]-7-tetrahydropyran-4-yl-3H-imidazo[5,1-f][1,2,4]triazin-4-one

SMILES O=c1[nH]c(CN2CC(C2)Oc2cccnc2)nn2c(ncc12)C1CCOCC1

InChI Key InChIKey=QYWRANXKUULQSK-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 247220   

LigandPNGBDBM247220(US9434733, 2-[[3-(3-pyridyloxy)azetidin-1-yl]methy...)
Affinity DataIC50: 350nMT: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2017
Entry Details
Go to US Patent

LigandPNGBDBM247220(US9434733, 2-[[3-(3-pyridyloxy)azetidin-1-yl]methy...)
Affinity DataIC50: 350nMpH: 7.6 T: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2017
Entry Details
Go to US Patent

LigandPNGBDBM247220(US9434733, 2-[[3-(3-pyridyloxy)azetidin-1-yl]methy...)
Affinity DataIC50: 350nMpH: 7.6 T: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2018
Entry Details
Go to US Patent

LigandPNGBDBM247220(US9434733, 2-[[3-(3-pyridyloxy)azetidin-1-yl]methy...)
Affinity DataIC50: 36nMAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2020
Entry Details
Go to US Patent

LigandPNGBDBM247220(US9434733, 2-[[3-(3-pyridyloxy)azetidin-1-yl]methy...)
Affinity DataIC50: 5.28E+3nMAssay Description:PDE1 assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzym1 (sufficient to con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2020
Entry Details
Go to US Patent