BDBM247206 US10513524, Compound (P4)::US11608342, Compound (P4)::US20250019381, Compound (P4)::US9434733, 2-[[3-[(4-fluorophenyl)methoxy]azetidin-1-yl]methyl]-7-tetrahydropyran-4-yl-3H-imidazo[5,1-f][1,2,4]triazin-4-one::US9533992, 2-[[3-[(4-fluorophenyl)methoxy]azetidin-1-yl]methyl]-7-tetrahydropyran-4-yl-3H-imidazo[5,1-f][1,2,4]triazin-4-one

SMILES Fc1ccc(COC2CN(Cc3nn4c(ncc4c(=O)[nH]3)C3CCOCC3)C2)cc1

InChI Key InChIKey=QEJJXMNBAFWGJK-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 247206   

LigandPNGBDBM247206(US9434733, 2-[[3-[(4-fluorophenyl)methoxy]azetidin...)
Affinity DataIC50: 10nMT: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2017
Entry Details
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LigandPNGBDBM247206(US9434733, 2-[[3-[(4-fluorophenyl)methoxy]azetidin...)
Affinity DataIC50: 10nMpH: 7.6 T: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2017
Entry Details
Go to US Patent

LigandPNGBDBM247206(US9434733, 2-[[3-[(4-fluorophenyl)methoxy]azetidin...)
Affinity DataIC50: 10nMpH: 7.6 T: 2°CAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/18/2018
Entry Details
Go to US Patent

LigandPNGBDBM247206(US9434733, 2-[[3-[(4-fluorophenyl)methoxy]azetidin...)
Affinity DataIC50: 10nMAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2020
Entry Details
Go to US Patent

LigandPNGBDBM247206(US9434733, 2-[[3-[(4-fluorophenyl)methoxy]azetidin...)
Affinity DataIC50: 1.01E+3nMAssay Description:PDE1 assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzym1 (sufficient to con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2020
Entry Details
Go to US Patent

LigandPNGBDBM247206(US9434733, 2-[[3-[(4-fluorophenyl)methoxy]azetidin...)
Affinity DataIC50: 10nMAssay Description:A PDE9 assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
Go to US Patent

LigandPNGBDBM247206(US9434733, 2-[[3-[(4-fluorophenyl)methoxy]azetidin...)
Affinity DataIC50: 1.01E+3nMAssay Description:PDE1 assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzym1 (sufficient to con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
Go to US Patent

LigandPNGBDBM247206(US9434733, 2-[[3-[(4-fluorophenyl)methoxy]azetidin...)
Affinity DataIC50: 10nMAssay Description:Non-limiting examples of PDE9 inhibitors of formula (II) are disclosed in WO 2013/110768, the contents of which are incorporated herein by reference ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2025
Entry Details
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LigandPNGBDBM247206(US9434733, 2-[[3-[(4-fluorophenyl)methoxy]azetidin...)
Affinity DataIC50: 1.01E+3nMAssay Description:Non-limiting examples of PDE9 inhibitors of formula (II) are disclosed in WO 2013/110768, the contents of which are incorporated herein by reference ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2025
Entry Details
Go to US Patent