BDBM2472 13-chloro-2-thia-3,9-diazatricyclo[8.4.0.0^{3,7}]tetradeca-1(10),4,6,11,13-pentaene-2,2,8-trione::Pyrrolobenzothiadiazepine (PBTD) 11i

SMILES Clc1ccc2NC(=O)c3cccn3S(=O)(=O)c2c1

InChI Key InChIKey=KWJGLOYDUZSVJG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 2472   

TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Sapienza University of Rome

LigandPNGBDBM2472(13-chloro-2-thia-3,9-diazatricyclo[8.4.0.0^{3,7}]t...)
Affinity DataIC50: 700nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2004
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Institute of Experimental Botany Ascr & Palack£

Curated by ChEMBL
LigandPNGBDBM2472(13-chloro-2-thia-3,9-diazatricyclo[8.4.0.0^{3,7}]t...)
Affinity DataIC50: 700nMAssay Description:Inhibition of HIV1 reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed