BDBM24719 13-methyl-8,11,12-triazatetracyclo[7.6.0.0^{2,7}.0^{10,14}]pentadeca-1(9),2,4,6,10,13-hexaene::dihydropyrazolocyclopentaindole, 21

SMILES Cc1[nH]nc-2c1Cc1c-2[nH]c2ccccc12

InChI Key InChIKey=JHGGFQICWDUZTH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 24719   

TargetAurora kinase A(Human)
Genentech

LigandPNGBDBM24719(13-methyl-8,11,12-triazatetracyclo[7.6.0.0^{2,7}.0...)
Affinity DataIC50: 870nMpH: 7.5 T: 2°CAssay Description:Aurora kinase was assayed in ELISA format using a GST fusion of the N-terminus of Histone H3 as substrate. Plates were coated with substrate, and the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2008
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Genentech

LigandPNGBDBM24719(13-methyl-8,11,12-triazatetracyclo[7.6.0.0^{2,7}.0...)
Affinity DataIC50: 880nMpH: 7.5 T: 2°CAssay Description:Aurora kinase was assayed in ELISA format using a GST fusion of the N-terminus of Histone H3 as substrate. Plates were coated with substrate, and the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2008
Entry Details Article
PubMed