BDBM24711 7,7-dimethyl-2-(5-methyl-1H-pyrazol-3-yl)-1H,5H,6H,7H-imidazo[4,5-f]indol-6-one::Lactam analogue, 1

SMILES Cc1cc(n[nH]1)-c1nc2cc3c(NC(=O)C3(C)C)cc2[nH]1

InChI Key InChIKey=DRKOUHSEDVEHEG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 24711   

TargetAurora kinase A(Human)
Genentech

LigandPNGBDBM24711(7,7-dimethyl-2-(5-methyl-1H-pyrazol-3-yl)-1H,5H,6H...)
Affinity DataIC50: 180nMpH: 7.5 T: 2°CAssay Description:Aurora kinase was assayed in ELISA format using a GST fusion of the N-terminus of Histone H3 as substrate. Plates were coated with substrate, and the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2008
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Genentech

LigandPNGBDBM24711(7,7-dimethyl-2-(5-methyl-1H-pyrazol-3-yl)-1H,5H,6H...)
Affinity DataIC50: 150nMpH: 7.5 T: 2°CAssay Description:Aurora kinase was assayed in ELISA format using a GST fusion of the N-terminus of Histone H3 as substrate. Plates were coated with substrate, and the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2008
Entry Details Article
PubMed